Pool make the long trip to the capital to face Leyton Orient in League One.
Orient are without defender John Mackie who has a foot injury, forward Echanomi is out with a knock on a knee and Micheal Simpson also has a knee injury.
They do have defender Gary Alexander back after a suspension and Adam Tann could return after surgery after being diagnosed with testicular cancer.
Orient currently are one place above the relegation zone and have gone for five games without a win.
The young striker is on loan from Charlton and has bagged 3 goals this season, one of those goals came in his loan spell with Bristol Rovers. He`s made eight appearances for the Orient.
Grayson might be able to call upon Wes Hoolahan who`s been out with back and calf problems.
Ian Evatt is back from a one-match suspension which means Kaspars Gorkss may move over to left back to allow Evatt to resume his partnership alongside Michael Jackson.
The ever willing Morrell broke the deadlock last week and will look to continue his scoring form in the match on Saturday. He`s bagged 11 goals so far this season with three coming in the last two matches.
Earlier in the season Pool laid Orient out to dry winning at a canter 3-0. Morrell, Hoolahan and Parker the scorers with Tann being sent off for the O`s.
The last time Pool visited Brisbane Road was in 2001 in League Two, Pool lost out that day 1-0 with Matty Lockwood with a second half winning strike.
You have to go back to 1995 for the last time Pool recorded a vicoty against Orient in the capital when a Andy Watson goal separated the two sides.
R L Lewis – Shrewsbury – Games: 17 Yellow Cards: 63 Red Cards: 3
S P Beck and C J Francis
Fourth Official : D D Bushell
Orient 1 – 2 Pool
English FA Cup Norwich H 27-01-2007